Skip to Content

Stock photo from Pixabay

Pfizer develops new oral medicine against Covid-19

The pharmaceutical company Pfizer has launched the first trials of people with an experimental drug to treat Coronavirus infections. The medicine, which is administered in the form of pills or intravenously, is thought to be able to stop the Coronavirus from copying itself - and thus provides protection against increased infection regardless of whether the patient is vaccinated or not.

Published: March 26, 2021, 8:01 am

    At present, there are only two treatment options for Covid-19, either an immune response, that is, the body’s own immune system attacks and fights the viral infection, or a treatment of the symptoms when the infection is already underway.

    While vaccines and good health can facilitate the body’s own ability to deal with the infection, medical treatments have been few. Remdesivir is currently the only drug-approved treatment and the effects are, just like the side effects, disputed. In SARS-COV-2 mutations in a patient with a persistent viral load treated with convalescent patient plasma and Remdesivir, resulted in no less than 7 mutations in the spike (including N501Y of the English and South African variant), and decreased sensitivity to antibodies occurred, a new study showed.

    But a third course of treatment may be on the way. The pharmaceutical company Pfizer announced on Tuesday that it has begun its phase-1 study of its new drug, PF-07321332, which is an orally administered antiviral drug against Covid-19. In addition, it is thought to be able to work against all variants of Coronavirus – including the mutations that continuously appear and risk making the vaccine unusable.

    Addressing the COVID-19 pandemic requires both vaccine prevention and targeted treatment for those affected by the virus. Given the SARS-CoV-2 mutation and the continuing global impact of COVID-19, it seems likely that access to therapeutic options both now and beyond the pandemic will be crucial, said Dr. Mikael Dolsten, Pfizer’s lead researcher, in a press release.

    The medicine comes in pill form and is a so-called protease inhibitor. It is a form of medication that has been used for a long time as antiviral drug, for example in HIV medications and in what is often called antidepressants. PF-07321332 acts similarly to these by preventing the production of an enzyme, in this case one that all Coronaviruses, including SARS-CoV-2, need to be able to initiate their copying process in our cells.

    When a virus enters the body, it injects genetic material through cell membranes and this causes the virus to “take over” the cells and cause them to produce more viruses, which in turn spread to other cells and repeat the process until we become ill or our immune system manages to fight them.

    By blocking that process, one succeeds in preventing the virus from spreading further in the body, which gives the immune system significantly greater opportunities to fight the infection. What this means in practical terms is that the medicine is given when an infection has been detected, preferably as early as possible in the infection, and thus the symptoms become less serious. Fewer affected cells cause fewer symptoms, less spread in the body with a less severe immune response – something that in itself can be harmful to the patient.

    “We have designed PF-07321332 as a potential oral treatment that could be prescribed at the first sign of infection, without the patients being in hospital or in critical care. At the same time, Pfizer’s intravenous antiviral candidate is a potential new treatment option for patients in hospitals. Together, the two have the potential to create a start-to-end treatment paradigm that complements vaccination in cases where the disease still occurs,” continued Dr. Dolsten.

    According to initial studies conducted by Pfizer, their medicines have shown a significant inhibitory effect on the SARS-CoV-2 virus, but also other variants of Coronavirus, as well as several different mutations of SARS-CoV-2. In addition to the pill form, an intravenous solution is also being developed that will be given in more severe cases of infection. The Phase-1 study begins with a small number of volunteers and will be conducted in the United States in the spring. After that, it is hoped to be able to start phase 2 studies with more participants already during the summer or no later than the beginning of autumn.

    Pfizer believes that the combination of the drug in its two different forms could mean a significant advance in the fight against the pandemic, but that it will not in itself be able to replace a mass vaccination program – which is a given since the company will earn billions from its own vaccine against Covid-19.

    Consider donating to support our work

    Help us to produce more articles like this. FreeWestMedia is depending on donations from our readers to keep going. With your help, we expose the mainstream fake news agenda.

    Keep ​your language polite​. Readers from many different countries visit and contribute to Free West Media and we must therefore obey the rules in​,​ for example​, ​Germany. Illegal content will be deleted.

    If you have been approved to post comments without preview from FWM, you are responsible for violation​s​ of​ any​ law. This means that FWM may be forced to cooperate with authorities in a possible crime investigation.

    If your comments are subject to preview ​by FWM, please be patient. We continually review comments but depending on the time of day it can take up to several hours before your comment is reviewed.

    We reserve the right to del​ete​ comments that are offensive, contain slander or foul language, or are irrelevant to the discussion.


    Swiss epidemiologist warns against US Covid vaccination strategy as only option

    GenevaSwiss epidemiologist Antoine Flahault warned of the risks of the strategy focused on vaccination with current vaccines alone as a solution. He cited the example of the United States.

    WEF involved in non-white manufacturers displaying new shelf labelling

    It seems to be part of the globalist agenda where the World Economic Forum once again appears in the background after a large food chain in the United States joined the Woke movement, now rolling over the declining superpower like an unstoppable steamroller. Labels such as "black-owned", "Latin-owned", "LGBTQ-owned" and so on is being displayed to encourage customers to buy these at the expense of "white-owned" companies.

    Texas and Florida prohibit federal vaccination certificates

    The US state of Texas has banned state-mandated vaccination certificates. On Tuesday, Republican Governor Greg Abott introduced an executive order to prohibit any regulation requiring Texans to show proof of vaccination before receiving a product or service.

    Boulder’s mass killer not a ‘white domestic terrorist’ but a product of media bias

    The mass shooter who killed ten people in Boulder, Colorado, is not a "white domestic terrorist", but a Syrian immigrant. He has been identified by American law enforcement as the 21-year-old Ahmad al-Aliwi al-Issa.

    US foreign policy is constructed around the ‘baizuo’ ideology

    BeijingBaizuo is a rough translation from Mandarin which means "white liberal". American foreign policy is driven by people who answer to the description of this Chinese neologism, a political epithet pejoratively used to refer to self-debasing Western ideology primarily espoused by white leftists.

    Wrong skin colour: Second white translator kicked out by Biden’s poet laureate

    BarcelonaOnce again, a translator of the poem that the black American writer Amanda Gorman recited at the inauguration of US President Joe Biden has been relieved of his duties. The Catalan writer Victor Obiols said he was pulled from the job because he had the wrong racial "profile".

    Biden’s border crisis

    The US states of Arizona and Montana are taking legal action to block new Biden administration immigration regulations. The crisis at the southern US border started brewing at the end of 2020 because the human and drug trafficking cartels expected President Joe Biden to have a “hands-off” attitude.

    Is the ‘leader of the free world’ in hiding?

    WashingtonWhite House press secretary Jen Psaki said last week that unlike his predecessors, US President Joe Biden will not be participating in any live press conference in the near future. Biden has increasingly come under fire for not holding a formal press conference and taking questions even from carefully selected reporters in the six weeks since taking office.

    Mississippi, Texas lift Corona restrictions

    JacksonMississippi Republican Governor Tate Reeves announced on March 2 on Twitter that he will now lift the current restrictions imposed on various businesses in his state in the Southeastern region of the United States.

    United States: White farmers deprived of aid to reduce their debt

    WashingtonPresident Joe Biden's federal aid program only offers “socially disadvantaged” farm owners who are victims of “historic discrimination” hundreds of thousands of dollars.

    Go to archive