Arthritis drug against Covid-19 shows promising results
In Brescia, Italy, some 100 Covid patients with severe respiratory problems treated with Tocilizumab, an anti-arthritis drug, showed improvement in 77 percent of cases.
Published: April 22, 2020, 8:59 am
Tocilizumab, an anti-arthritis drug being tested also against Coronavirus, has been giving positive results after more than two-thirds of patients treated improved or stabilized.
The drug was created with another clinical purpose, that of treating superinflammation in diseases such as rheumatoid arthritis. The results are from the first hundred patients with the virus treated at the Asst Spedali Civili in Brescia with severe respiratory failure.
Italian daily la Repubblica reported that within 24-72 hours and 10 days after administration of Tocilizumab, improvement of acute respiratory distress syndrome was assessed using scores ranging from 0 to 8 in order of increasing severity.
Nicola Latronico of the Anesthesia and Resuscitation Unit 2 and spokesperson for the study, said out of 100 patients 43 received Tocilizumab in the intensive care unit, and 57 outside the intensive care unit due to unavailability of beds. “Of these 57 patients, 37 (65 percent) improved and discontinued non-invasive ventilation, seven (12 percent) remained stable in the intensive care unit and 13 (23 percent) worsened (10 deaths, 3 hospitalized in intensive care).”
Overall, the respiratory condition improved or stabilized in 77 patients at 10 days, of whom 61 showed a significant reduction in lung injury and 15 were discharged from the hospital, the expert said.
Thanks to these results, the drug will undoubtedly also be used in numerous other patients given the lack, at the moment, of other available drugs.
Moreover, laboratory testing on Tocilizumab have shown in all patients very high levels, sometimes even out of scale, of reactive protein C (Pcr), ferritin, D-Dimer and triglycerides, confirming the hypothesis that a hyper-inflammatory disease present when patients’ respiratory conditions worsened and confirming the rationale for using Tocilizumab.
The study was carried out by a group of specialists in Anesthesia and Resuscitation, Infectious Diseases, Rheumatology, Pediatrics, Clinical Biochemistry and Immunology of the University of Brescia, and will be published in the July issue of Autoimmunity Reviews magazine.
The Pascale Institute in Naples was the first to show excellent results on two hospitalized Chinese patients and on four others who had been extubated after the drug was administered. Hospital doctors had launched an appeal to validate the positive results of Tocilizumab.
In addition, China in recent weeks noted that Tocilizumab could be a valid treatment and it was defined as “effective” at the Anhui Provincial Hospital as well as the Anhui Fuyang Hospital.
All rights reserved. You have permission to quote freely from the articles provided that the source (www.freewestmedia.com) is given. Photos may not be used without our consent.
Consider donating to support our work
Help us to produce more articles like this. FreeWestMedia is depending on donations from our readers to keep going. With your help, we expose the mainstream fake news agenda.
Keep your language polite. Readers from many different countries visit and contribute to Free West Media and we must therefore obey the rules in, for example, Germany. Illegal content will be deleted.
If you have been approved to post comments without preview from FWM, you are responsible for violations of any law. This means that FWM may be forced to cooperate with authorities in a possible crime investigation.
If your comments are subject to preview by FWM, please be patient. We continually review comments but depending on the time of day it can take up to several hours before your comment is reviewed.
We reserve the right to delete comments that are offensive, contain slander or foul language, or are irrelevant to the discussion.
BaselThe city of Basel offers a travel voucher to beggars who, in exchange, undertake not to return to the city for at least a certain period of time under penalty of permanent expulsion from the country.
RambouilletIn the wake of the murder of Samuel Paty, the Tunisian jihadist involved in the Rambouillet beheading wrote on Facebook: “O Muslims, now we will respond to the insults from France.” Two months later, he obtained his residence permit.
SheffieldSir Isaac Newton's historical legacy amounts to “colonial-era activity” and must be scrapped to “decolonise” the engineering curriculum at Sheffield University in the UK.
KasselWith its special edition “Antifa - The underground leftist power”, COMPACT, a conservative German magazine has stirred up a hornets' nest. A left-wing politician even wants to have journalistic research banned.
BerlinA confidential report by the German Federal Intelligence Service (BND), revealed how the Nigerian mafia has taken root to establish itself in Germany through the influx of migrants. There are now several different Mafia groups operating in Germany.
BrusselsWith the dominant position the EU has granted to Pfizer, in particular by ruling out the Russian Sputnik V vaccine, it is once again proving that its rules are of variable geometry because European treaties outlaw monopolies.
ParisThe lack of commitment on the left in the Sarah Halimi affair in France, has deeply shocked many. The murderer of Sarah Halimi, Kobili Traoré, will not be tried for his crime, according to his judges. But the victim is also being killed for a second time by silence.
MoscowThe Arctic region is facing demographic decline and climate challenges and beyond that, economic value creation through Arctic technologies and innovations which are dependent on a transforming geopolitical context.
In the shadow of the Corona crisis, the surveillance state in Germany is being systematically expanded. The controversial Palantir software, which was also created with funds from the CIA, has once again attracted negative attention. The monitoring software is already being used by the state police in Hesse and North Rhine-Westphalia (NRW).
ParisAccording to the results of a survey carried out by OnePoll for ExpressVPN and relayed by CNews, approximately 72 percent of French people are worried about the implementation of a vaccine passport. At the same time, less than half of the respondents are ready to use it.