Skip to Content

Vaccine. Stock photo from Pixabay
Göttingen

Vaccine-immune Corona variants conceivable say researchers

Corona variants, against which current vaccines are less effective or no longer effective at all, can also arise in Germany, according to researchers. This is particularly possible with the virus spreading in a third wave, according to Stefan Pöhlmann and Markus Hoffmann from the Leibniz Institute for Primate Research in Göttingen.

Published: April 14, 2021, 6:19 am

    Read more

    According to the information, such escape variants can arise if the virus spreads in a population with incomplete immune protection. This is also the case, for example, if the immunity slowly decreases after surviving an infection or vaccination.

    In a population with a certain degree of immunity, escape variants would have an advantage over the original virus with comparable infectivity, explained Pöhlmann and Hoffmann. In such a scenario, an escape variant would become dominant relatively quickly. An example could be the mutant P.1 in Brazil.

    “If there is hardly any immunity in a population, as is currently the case in Germany, an escape variant would be in direct competition with the predominant virus variants, which in turn still find enough susceptible hosts,” the scientists explained.

    Then an escape variant would only prevail over a large area if it was also easier to transfer.

    The experts from the German Primate Center, together with colleagues from the Ulm University Hospital, discovered that an antibody used for Covid-19 therapy was completely ineffective in variants B.1.351 (South Africa) and P.1. They are classified as escape variants. It can be assumed, however, that B.1.351 and P.1 would still be inhibited by the available vaccines.

    “However, the vaccination protection may be reduced and of shorter duration.”

    It is therefore all the more important to quickly achieve large-scale immunity in the population through vaccination and thus deprive the host variants that they need to spread, they argued.

    In order to improve the protection against variants such as B.1.351 and P.1, the existing vaccines could be adapted. “This procedure would be similar to the vaccination strategy with which we protect ourselves against flu viruses,” explained Pöhlmann and Hoffmann.

    The emergence of variants that are no longer inhibited by vaccines that are now available is “an extreme scenario, but cannot be ruled out”. In order to reduce the likelihood that escape variants will arise, the spread of the virus must be effectively contained – for example by complying with the AHA rules and vaccination across the board.

    The researchers echoed the concerns of French epidemiologist Professor Didier Raoult, who has warned of the emergence of variants especially as a result of mink breeding since these animals are highly susceptible to the Coronavirus, which spreads rapidly to humans – the most likely initial source of infection. Both Denmark and Sweden have suspended mink farming after outbreaks of Covid-19.

    As of January 2021, the virus had been found at 400 mink farms in at least eight countries in the EU and European Economic Area – 290 in Denmark, 69 in the Netherlands, 17 in Greece, 13 in Sweden, three in Spain, two in Lithuania and one each in France and Italy. In France, the region of Brittany has been affected by a variant associated with these animals.

    In March, French health authorities warned against this variant after eight infected patients died, ARS Bretagne announced.

    In a press release, the Directorate General of Health specified that its discovery was made as part of the monitoring of the cluster at Lannion hospital, in Côtes-d’Armor. “On March 13, 79 cases were identified, including 8 cases carrying the variant, confirmed by sequencing”.

    The variant was placed in the VUI (Variant Under Investigation) category of the World Health Organization (WHO) because nasopharyngeal tests do not detect it. Indeed, the PCR tests corresponding to the 8 carriers of the variant were all negative. To detect it, healthcare professionals had to use serological tests or deep breathing samples.

    At the end of last month, the prefect of Brittany and the local ARS announced that the 8 patient carriers had died. However, they “have not yet established the link between the variant and their deaths”.

    Pierre Tattevin, head of the infectious diseases department at Rennes University Hospital, has alluded to “dozens of cases” and “deaths” on BFM TV due to the difficulty of carrying out the follow-up and the tracing of the positive cases: “The PCR tests are negative […] because the patients do not excrete it at the level of the nose, since when one takes deeper samples – for example when the patients are in intensive care and need lung samples, at that time the test is positive.”

    In his weekly bulletin on YouTube, Raoult also urged regulators to ban Remdesivir as a treatment for Covid because it acts as a variant multiplier.

    Consider donating to support our work

    Help us to produce more articles like this. FreeWestMedia is depending on donations from our readers to keep going. With your help, we expose the mainstream fake news agenda.

    Keep ​your language polite​. Readers from many different countries visit and contribute to Free West Media and we must therefore obey the rules in​,​ for example​, ​Germany. Illegal content will be deleted.

    If you have been approved to post comments without preview from FWM, you are responsible for violation​s​ of​ any​ law. This means that FWM may be forced to cooperate with authorities in a possible crime investigation.

    If your comments are subject to preview ​by FWM, please be patient. We continually review comments but depending on the time of day it can take up to several hours before your comment is reviewed.

    We reserve the right to del​ete​ comments that are offensive, contain slander or foul language, or are irrelevant to the discussion.

    Europe

    Italy: Nationwide house raids against vaccine opponents

    MilanThe Milan Public Prosecutor's Office has launched searches of anti-vaccination opponents in six Italian cities. Allegedly the members of the Telegram group "The Warriors" planned violent demonstrations against the Covid-19 policy of the Italian government.

    Orban offers Pope copy of 1250 letter in which a Hungarian king pleads for help against Tartar invasion

    BudapestDuring his visit to Budapest on Sunday to celebrate mass, Pope Francis met with Hungarian Prime Minister Viktor Orban, whose anti-migration policy in Hungary he does not share. The Pope received a copy of a letter reminding him why he should be more circumspect in his views.

    EMA: Almost a third of Covid vaccination side effects are severe

    BrusselsThe reported suspected side effects for the four Covid vaccines, which have only been conditionally approved in the EU, are record-breaking after just 8 months. Serious side effects have been reported.

    Breaking news: UK government drops Covid passport

    LondonIn the UK, Health Minister Sajid Javid has told the BBC that Covid passports will not be introduced in his country. When will European countries come to their senses?

    France: Thousands protest against ‘health pass’ for 9th weekend in a row

    ParisOn Saturday, demonstrators took to the streets in the French capital for the ninth consecutive weekend to express their displeasure with the health passport policy of the Macron administration. The protest quickly degenerated into clashes with the police.

    Key Dutch ministers in bed with the WEF

    The HagueAt the end of May, the Forum for Democracy led by Thierry Baudet, submitted a parliamentary question on the relations between cabinet members and Klaus Schwab's World Economic Forum. "We received evasive or even no answers to these questions," said Dutch MP Pepijn van Houwelingen.

    Marine Le Pen’s phone number leaked on social networks

    ParisThe cellphone number of the president of the National Rally was published on social networks. Many strangers called her, forcing her to change her number and file a complaint.

    Hungarian teacher promises better grades to vaccinated children

    TamasiParents have complained about the biology teacher at the Würtz Ádám Primary School and Elementary Art School in Tamasi, Hungary, because he wanted to reward students who had been vaccinated against the Coronavirus and punish those who had not received the jab.

    Serious vaccination side effects increase by a factor of 114 in Switzerland

    BernAccording to the Swiss regulatory authority, 137 people have died after the mRNA injections since the start of the vaccination campaign. And the serious side effects after the mRNA injections continue to increase.

    Opposition to compulsory vaccination at Swiss Air growing

    BernSwiss Air now requires that its employees be vaccinated by mid-November, but not everyone agrees. Several hundred employees have formed a group demanding more detailed clarifications because the vaccination could be a threat to flight safety.

    Go to archive